In your lifetime, what is the question you have asked most of yourself and why?
What is wrong with you? LOL!
Believe it or not, that probably is the truth. But in my saved life, the biggest one has been "What should I be doing right now--what is God's perfect will for me right now?" That question takes on many forms like, "What should I be learning from this adverse situation?" or, "How do I change my attitude to line up with what glorifies God even though I'm unhappy with whatever is going on" or, "What are some small doable steps I can take to turn this thing around and get it going in the right direction?"
I'm pretty hard on myself, but myself is pretty good at justifying herself when she doesn't want to change. So yeah, me and myself have some Paul-like arguments (that I would do, I do not; that which I hate, I do... Oh wretched [wo]man that I am!)